PDL1 (Immunotherapy) Tests
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| PDL1 (Immunotherapy) Tests : What is a PD-L1 Test? A PD-L1 test uses a sample of cancerous tumor tissue to measure how much of a protein called PD-L1 is found on the cancer cells. If you have certain types of cancer, PD-L1 testing can check whether you may benefit from a type of cancer treatment called immunotherapy. Immunotherapy helps your own immune system fight cancer. Normally, PD-L1 is found on certain healthy cells. It acts as a kind of "brake" to stop cells in your immune system, called T cells, from attacking healthy cells in your body. If cancer cells have high amounts of PD-L1, they can turn your T cells off so they can't attack the cancer cells. If high amounts of PD-L1 are found on cancer cells, immunotherapy medicines called "immune checkpoint inhibitors" may be used. These medicines prevent the PD-L1 protein from putting the brakes on T cells. This frees your T cells to fight cancer. Immunotherapy can help stop or slow the growth of many types of cancers that have PD-L1. Immunotherapy has fewer side effects than cancer chemotherapy. But it can cause serious side effects in some people, and not everyone benefits from it. There are many types of PD-L1 tests. The test your health care provider orders will depend on: - The type of cancer you have - The specific immunotherapy medicine that your provider is considering for you Other names: programmed death-ligand 1, PDLI, PDL-1 by immunohistochemistry (IHC) | |
| Review Date: 14/12/2022 | Updated By: |