Sex-linked recessive
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Dados do National Institutes of Health
| Sex-linked recessive : Sex-linked diseases are passed down through families through one of the X or Y chromosomes. X and Y are sex chromosomes. Dominant inheritance occurs when a variant gene from one parent causes disease, even though the matching gene from the other parent is normal. The variant gene dominates. But in recessive inheritance, both matching genes must be variant to cause disease. If only one gene in the pair is variant, the disease does not occur or it is mild. Someone who has one variant gene (but no symptoms) is called a carrier. Carriers can pass variant genes to their children. The term "sex-linked recessive" most often refers to X-linked recessive. | |
| Review Date: 31/03/2024 | Updated By: Updated by: Anna C. Edens Hurst, MD, MS, Associate Professor in Medical Genetics, The University of Alabama at Birmingham, Birmingham, AL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. |