Syphilis Tests
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Dados do National Institutes of Health
| Syphilis Tests : What are syphilis tests? Syphilis tests generally look for certain antibodies in your blood. Antibodies are proteins that your immune system makes when it finds harmful substances in your body. In this case, the harmful substance is the bacterium that causes syphilis, one of the most common sexually transmitted infections (STIs.) Testing usually involves two steps. The first is used to screen for antibodies that your immune system makes in response to syphilis, some autoimmune diseases, and other infections. The two most common types of this test are: - Rapid plasma reagin (RPR), which is a blood test that looks for an antibody called reagin. Your body often makes reagin in response to a syphilis infection. - Venereal Disease Research Laboratory (VDRL) Test, which can be done on blood or spinal fluid. This test looks for a broader range of antibodies that your immune system might make in response to a syphilis infection. The second step in syphilis testing is to confirm the findings of the first step. If the result of your screening test shows you have antibodies linked to syphilis infections, you'll need a second test to confirm whether you have syphilis. Usually, the second test looks for antibodies that your immune system makes only to fight off syphilis. If you have these antibodies, it means you either currently have a syphilis infection or had a syphilis infection that's been treated. In some cases, a health care provider will use a test that looks for actual syphilis bacteria, instead of antibodies. These tests are less common because they can only be done in specialized labs. Other names: rapid plasma reagin (RPR), Venereal Disease Research Laboratory (VDRL), fluorescent treponemal antibody absorption (FTA-ABS) test, agglutination assay (TP-PA), darkfield microscopy, Treponema pallidum particle agglutination assay (TP-PA), Fluorescent treponemal antibody absorption (FTA-ABS) test, Microhemagglutination assay for antibodies to T. pallidum (MHA-TP), T. pallidum hemagglutination assay (TPHA), T. pallidum enzyme immunoassay (TP-EIA), Chemiluminescence immunoassays (CLIA) | |
| Review Date: 08/07/2025 | Updated By: |